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HR Information

How learning and development will change in 2014

Learning and development (L&D) is set to undergo a series of changes in 2014 as it assumes a greater priority for organisations looking to capitalise on improved economic conditions.

Due to the economic recovery, organisations are likely to look at their learning and development budgets, reports Personnel Magazine. Many departments suffered cutbacks when the recession was at its worst – but staff will begin to demand more engagement after having to take on increased workloads for little extra reward.

"Employees are now looking to put their careers back on track, so they’re starting to expect an investment in them in terms of their development," said Steve Morris, business development director at learndirect. "They’re now saying, 'you should be developing me'."

There will be a shift in L&D systems away from the large-scale training schemes which involve annual appraisals towards a fluid and dynamic approach which employees can apply immediately.

A key priority for L&D will be developing capable, resilient and adaptable leaders. Much of organisations' previous focus has been on the training of graduates and top-level employees. 

Consulting company a&dc found 28 per cent of employers felt they were ineffective at developing their "middle layer" of future leaders – the group which has arguably been hardest-hit by the downturn.

Apprenticeships are likely to form another important area of organisations' employment strategies. Research by the Department for Business, Innovation and Skills attests to the value of apprentices, which boost productivity levels by £214 per week in return for only a modest salary.

Advances in technology will affect the way L&D is delivered. E-learning is likely to play a much bigger role, in place of traditional instructor-led courses, according to Ruth Stuart, L&D adviser at the Chartered Institute of Personnel and Development. In addition, learner-centred, social and collaborative methods will be given greater prominence.

Technology will also change the way L&D is recorded, measuring how learners absorb knowledge. Informal platforms will enable employees to share information with one another and managers will be able to monitor this practice. As a consequence of these trends, continual monitoring of development will displace the traditional focus on methods such as annual appraisals.

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Microbiology

Scientists demonstrate how immune system combats cancer

Scientists have discovered a mechanism which enables the body to combat cancerous immune B cells before they develop into cancers. The new research could help to develop early intervention techniques for people at risk of developing the disorder.

Research conducted at the Walter and Eliza Hall Institute found the immune system is responsible for eliminating potentially cancerous B cells before they develop into B cell lymphomas. Their findings are published in the latest edition of the journal Nature Medicine.

According to the research team, the results of the study account for the relative rarity with which B-cell lymphomas occur in the general population, considering the high frequency of these mutations in the general population. It could lead to the development of an early warning system which identifies patients at risk of developing these cancers. 

Dr Axel Kallies, associate professor David Tarlinton, Dr Stephen Nutt and colleagues carried out the research. Dr Kallies said a paradox had existed relating to the rarity of the incidence of such cancers given the high frequency of mutations. "Our finding that immune surveillance by T cells enables early detection and elimination of these cancerous and pre-cancerous cells provides an answer to this puzzle, and proves that immune surveillance is essential to preventing the development of this blood cancer," he commented.

Some 2,800 people a year develop B cell lymphoma in Australia, where it is the most common form of blood cancer. Patients with a weakened immune system are at a particularly high risk of developing the disease.

The discovery was made when the research team was investigating how B cells change during the development of lymphoma. T cells were disabled in order to depress the immune system and under these conditions lymphoma developed in a matter of weeks rather than years.

Associate professor Tarlinton said the research would enable the development of a diagnostic system that identifies people in the early stages of the disease. Therapies already exist which can be used to remove these malfunctioning B cells in at-risk patients and once a test is developed it would not be long before it could be put to clinical use.

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HR Information

Female work satisfaction and promotion differences revealed

A new study has found that efforts to improve gender diversity in the workforce may be being hampered by focusing on issues that make women feel more satisfied rather than helping them achieve promotion.

According to the study, which surveyed 3,000 female and male professionals, the features of working life that provide women with career satisfaction are vastly different from those that drive career progression, HR Magazine reports. 

Critical job assignments, politically-skilled networking and risk-embracing seeking of opportunities are the factors which lead to women's career progression, according to IBM company Kenexa.

In terms of what makes them satisfied with career progression, women gave different responses. The answers given include having fair and objective HR processes in place to support promotion decisions as well as having a supportive line manager who believes in their potential. 

A clear plan about how to advance their career and achieve their goals also made women feel satisfied with their progression.

According to Kenexa senior psychologist at the High Performance Institute and report author Ines Wichert, the findings of the report could account for the slower progress of women to top positions. She points out that feeling satisfied with progression opportunities offers no guarantee of securing promotion.

"This could explain why many organisations struggle to see change as a result of their gender diversity initiatives – perhaps they are focusing on initiatives that make women feel more satisfied, but not on initiatives that drive actual promotions and therefore career progression for women," she commented.

Ms Wichert added that employers need to take this information into account when planning their gender diversity initiatives.

Campaign group Opportunity Now director Kathryn Nawrockyi said her studies show that companies with more women in leadership roles are twice as likely to have gender-focused objectives forming part of their diversity strategy.

Further findings of the report show that the "golden age" of career progression is considered to be between 28 and 34; thereafter, promotions and job satisfaction are said to decrease.

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Microbiology

Stem cell therapy used to treat lung disease

Research conducted at the Boston Children's Hospital has shown it may be possible to treat lung diseases by introducing proteins which instruct lung stem cells to produce the cell types needed to repair the injuries caused by such conditions.

A natural pathway exists in the lung which instructs stem cells to develop into specific types of cells. Researchers enhanced this natural pathway in a mouse model, successfully increasing production of alveolar epithelial cells, which line the small sacs (alveoli) where gas exchange takes place. Diseases such as emphysema and pulmonary fibrosis permanently damage these cells.
 
The researchers inhibited this pathway, causing increased production of airway epithelial cells, which are damaged by diseases that affect the lung's airways.

A 3D culture was developed to model the environment of the lung. It was found that a single lung stem cell could be made to produce alveolar and bronchiolar epithelial cells. When a protein known as thrombospondin-1 (TSP-1) was added to these cultures, they encouraged the stem cells to produce alveolar cells.

Experiments were conducted on a mouse model in which symptoms of fibrosis were induced. Endothelial cells, which line the lung's many small blood cells – and which naturally produce TSP-1 – were taken from the mice and liquid surrounding the cultured cells was injected into the mice. This process reversed the lung damage.

When the team used lung endothelial cells that lacked TSP-1 in the 3D cultures, it was discovered that the stem cells produced more airway cells. In live mice engineered to lack TSP-1, airway repair after injury was enhanced.

"When lung cells are injured, there seems to be a cross talk between the damaged cells, the lung endothelial cells and the stem cells," says Joo-Hyeon Lee, who is first author on the paper.

"We think that lung endothelial cells produce a lot of repair factors besides TSP-1," added the paper's senior author, Carla Kim. "We want to find all these molecules, which could provide additional therapeutic targets."

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Microbiology

Scientists make breakthrough in developing heart tissue

Researchers have successfully engineered cardiac tissue in the laboratory that could be used as an in vitro surrogate for human myocardium and for preclinical therapeutic screenings.

Tissue which bridges the gap between animals and human subjects has been developed in the laboratory for some organs but creating such models for the heart has proved elusive. The tissue developed in the new study was generated from human embryonic stem cells and the resulting muscle is significantly similar to human heart muscle.

The research, which was published in the February 2014 issue of The FASEB Journal, was conducted at the Cardiovascular Cell and Tissue Engineering Laboratory, Cardiovascular Research Center, Icahn School of Medicine at Mt. Sinai, in New York, NY. 

Researchers cultured human engineered cardiac tissue (hECTS) for seven to ten days. They self-assembled into a long, thin heart muscle strip that pulled on the end-posts and caused them to bend with each heartbeat. The tissue was thus exercised throughout the culture process.

Spontaneous contractile activity was displayed by the hECTS, in a similar manner to the human heart, and they responded to electrical stimulation. 

Some of the functional responses known to occur naturally in the adult human heart were also induced through electrical and pharmacological interventions. Some paradoxical responses displayed by the hECTS mimicked the behavior of the immature or newborn human heart.

It was also discovered that the hECTS were able to incorporate new genetic information carried by adenovirus.

Kevin Costa, one of the researchers at the Icahn School of Medicine, commented: "This could help revolutionise cardiology research by improving the ability to efficiently discover, design, develop and deliver new therapies for the treatment of heart disease, and by providing more efficient screening tools to identify and prevent cardiac side effects, ultimately leading to safer and more effective treatments for patients suffering from heart disease."

Gerald Weissmann, editor-in-chief of the FASEB Journal, said the new tissue model could be the best yet developed on which to test therapies and model deadly diseases.

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HR Information

BCC publishes skills manifesto

The British Chambers of Commerce (BCC) has set out a skills and employment manifesto designed to help the country address the skills shortage that could undermine future prosperity. 

According to the BCC, the proposals could radically transform the way people are educated and the way our adult workforce is trained. It advocates greater cooperation between the BCC and universities and SMEs to ensure young people receive the appropriate training and acquire skills relevant to the modern jobs market.

Employers consistently report a mismatch between the qualities they are looking for in their staff and the skills, experience and attitude displayed by prospective job candidates. Having the most skilled workforce possible will enable the country to compete in the global race.

Employability skills need to be at the heart of how schools are assessed and rated, according to the BCC. There also needs to be investment in careers education for all young people, including regular contact with different employers.

There need to be literacy, numeracy, computing and foreign languages qualifications which are clear and universally understood. Employers should be able to conduct an accurate appraisal of a candidate based on these qualifications.

Export skills and foreign languages should be encouraged by providing tax incentives and employment policy should be the responsibility of the Department for Business, Innovation and Skills.

In addition, universities should promote enterprise and ensure their courses are relevant to future job opportunities, the body stated.

Nora Senior, president of the BCC, said: "Although we believe that successive governments have failed our young people by not properly equipping them for their future careers, it is time to break away from the blame game. Various organisations and sectors continue to blame each other for a lack of ‘work readiness’ among young people but it is time for everyone to accept some responsibility, and find ways to move forward."

Ms Senior warned that if Britain does not keep up the pace with its competitors in a rapidly-changing world it could lose valuable business. However, she stressed that simple measures such as providing a good careers service can help put the country back on course for a prosperous future.

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Microbiology

Molecule could protect brain from diabetes damage

Diabetics' chances of developing dementia or Alzheimer's disease could be significantly reduced thanks to a new molecule created by researchers at the Hebrew University of Jerusalem.

High levels of sugar in the blood have been identified as a risk factor in dementia, impaired cognition, and a decline of brain function in diabetics and non-diabetics alike. The chance of diabetics developing Alzheimer's disease is twice as high as those not suffering from the disease.

A potential neuro-inflammatory pathway was discovered which could be responsible for the increased risk faced by diabetics and a possible treatment has also been identified.

A study was conducted on rats in an attempt to determine the mechanism responsible for changes in the brain due to high sugar levels. Diabetic rats were found to display high levels of enzymes called MAPK kinases, which facilitate cellular responses to a variety of stimuli, leading to inflammatory activity in brain cells and the early death of cells.

When the rats were injected with a sugar-lowering drug rosiglitazone for a month, they enjoyed a significant decrease in MAPK enzyme activity and a reduction in the inflammatory processes in the brain. The study's authors say this provides the first evidence of a functional link between high blood sugar and the activation of this specific inflammatory pathway in the brain.

A series of molecules called thioredoxin-mimetic peptides (TXM) has been developed by the study's leader, Professor Daphne Atlas, over the past few years. It mimics the action of thioredoxin and protects the cells from early death through activating inflammatory pathways. These were wound to prevent the action of MAPK kinases in animal models.

One of these molecules, TXM-CB3, significantly reduced the activity of these enzymes in the rats suffering from diabetes, reducing the accelerated brain cell death. This shows the molecule was able to traverse the blood-brain barrier and lower inflammatory processes in the animals' brains, despite the high blood sugar levels.

Professor Atlas said the discovery could lead to the development of preventive treatment in humans with high blood sugar levels.

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HR Information

‘More opportunities’ for HR staff in 2014

HR professionals are set to move during 2014, with 60 per cent expecting to look for a new job.

According to research conducted by recruitment company Hays, the resurgent strength of the UK economy means recruitment in the HR industry is set to increase during the next 12 months. 

Some 47 per cent of employers expect to hire more permanent HR staff and 28 per cent intend to take on additional temporary workers.

The findings are published in the Hays Human Resources Salary and Benefits Guide 2014. They are based on a survey of 570 employers and 780 employees.

Salaries for HR staff are forecast to increase in line with the cost of living by two-fifths of employers and 14 per cent of employers believe they will rise above inflation. More than half report having awarded pay rises during the past year.

HR generalists are expected to enjoy a growing number of opportunities, particularly within the £30,000 – £40,000 bracket. Opportunities will also abound for those in resourcing and talent, and reward roles.

HR advisors are predicted to earn an average salary of £28,000, while a salary of £77,000 will be available to HR directors.

There is expected to be a significant shortfall in experienced talent during the next 12 months. A shortage of such candidates is anticipated by 64 per cent of employers, while 41 per cent of employers believe their current business objectives are being compromised by a lack of talent. 

Barney Ely, director of Hays human resources, predicts a positive 2014 for the HR industry, with more opportunities available for staff. 

"It is evident that employers are now shifting from managing the challenges of the economic downturn to taking advantage of the growing confidence in the economy. This will increase competition for commercially astute HR professionals who can manage change, so employers will need to work hard to retain and attract the best talent to ensure their business can grow in 2014," he commented.

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Microbiology

Microtubule research could help develop cancer drugs

New research into the microscopic transport system that occurs within cells could help to develop new cancer treatments.

A critical point of failure in the microtubules, which act as a cellular transport system, was identified by researchers at Warwick Medical School.

Microtubules are 1,000 times thinner than a human hair and are used to transport molecules around cells. The study, published in Nature Communications, explains how these structures are targets for cancer drugs and how better treatments may be developed.

Narrow seams run down the length of microtubules, forming their weakest point. The structure dissolves if the seam cracks and splits.

Although scientists have been aware before now that microtubules have a single seam running along their length, the function of such a seam was not known. The Warwick researchers developed microtubules with extra seams in the laboratory and examined their stability using video microscopes. They found the structures become more unstable the more seams they have. 

The research has significantly altered thinking on the role of microtubules and scientists are now looking for factors inside the cell that influence the stability of microtubule seams

Some cancer therapy drugs target microtubules. Taxol, used in breast cancer therapy, prevents tumours from growing by binding to microtubules and stopping them from dissolving. This prevents microtubule tracks from remodelling themselves prior to cell division and stops them from dividing.

Professor Robert Cross, head of the research team at Warwick Medical School, explained: "It is clear that any new drugs aiming to stabilise or destabilise microtubules must target the microtubule seam. We expect this to lead us to a better understanding of the way microtubules are regulated in cells and why this sometimes goes wrong, such as in development of cancer."

He went on to say the insights the team have gained show how existing cancer drugs work and may lead to the development of more effective anti-microtubule drugs. Such drugs could have a significant impact on cancer treatment.

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HR Information

CEOs ‘should talk from the heart to promote gender equality’

CEOs should talk from their heart as well as their head in order to promote more equal roles between men and women, according to a new study.

Research conducted by KPMG and King's College London shows that merely outlining the business case for diversity is not sufficient to increase the number of women at senior levels. A more effective case can be made if CEOs talk from their heart as well as their head.

The study, carried out by Dr Elisabeth Kelan from the Department of Management at King’s, analysed how CEOs make the case for diversity within their organisations and the kind of leadership behaviours adopted in order to make change happen.

A number of factors are cited by CEOs as reasons for the lack of women at senior levels within organisations. Although "management failure" – shortcomings in systems, processes and people necessary to achieve equality – was the main reason, CEOs also believe women seek roles which enable them to achieve a greater balance between work and caring responsibilities.

Such attitudes risk stereotyping women's roles, as this sort of work-life balance is sought after by some women but not by all of them.

According to the findings of the research, CEOs often downplay the personal reasons for wanting more women in the workplace. In fact, they need to be more vocal about such reasons, as they often have strong women in their lives or other personal reasons for believing gender diversity at the top of organisations is a positive goal.

Dr Kelan said: "The current generation of CEOs has an opportunity to chart new territory in making progress on this issue and they need to understand the power of doing things with words. Through aligning their words and actions as much as their hearts with their heads, they can set their organisations on a trajectory that disrupts current practices and allows for sustainable change on gender parity."

Simon Collins, UK chairman of KPMG, said the research showed the conventional ways of addressing the problem of gender inequality are inadequate and discussing the issue of gender diversity in personal terms is the best way to make progress.